Do Firms Underinvest in Long-Term Research? Evidence from Cancer Clinical Trials

Do Firms Underinvest in Long-Term Research? Evidence from Cancer Clinical Trials

Coauthors: Benjamin J Roin and Heidi Williams
American Economic Review, (2015): 105, no. 7, 2044-2085. [PDF]

Abstract

We investigate whether private research investments are distorted away from long-term projects. Our theoretical model highlights two potential sources of this distortion: short-termism and the fixed patent term. Our empirical context is cancer research, where clinical trials — and hence, project durations — are shorter for late-stage cancer treatments relative to early-stage treatments or cancer prevention. Using newly constructed data, we document several sources of evidence that together show private research investments are distorted away from long-term projects. The value of life-years at stake appears large. We analyze three potential policy responses: surrogate (non-mortality) clinical-trial endpoints, targeted R&D subsidies, and patent design.

Awards

Winner- the Kauffman/iHEA Award for Health Care Entrepreneurship and Innovation Research
Winner- the Arrow Award for “best paper published in health economics” in 2015

Slides

Slides, Do Firms Underinvest in Long-Term Research?

Ben Roin and Heidi Williams
Seminar Slides, April 2015. [PDF]

Press Coverage

Why Preventing Cancer Is Not the Priority in Drug Development

New York Times, Austin Frakt, Dec 28, 2015 [PDF]


What Cures Are We Missing Out On?

Bloomberg, John Tozzi, Sep 30, 2015 [PDF]


Patents That Kill

The Economist, A.T., Aug 08, 2014 [PDF]


Why Aren’t There More Cancer Vaccines?

Slate, Ray Fisman, Aug 26, 2013 [PDF]