Patents and Innovation

This page collects my work related to patents and innovation. The 2015 AER paper with Roin and Williams remains one of my proudest professional accomplishments. We show theoretically and empirically that cancer research incentives are distorted towards treatment of late-stage disease and away from research on preventing cancer in the first place. This relates to broader concerns about incentives for long-horizon innovation versus so-called “short termism.”

Durvasula, Roin, Williams and I just released a new paper on what we call “Missing Markets for Innovation.” We show that there are large categories of potential innovation for which IP rights are ineffective and hence provide zero private-sector innovation incentives. The problem of New Uses of Existing Drugs is a canonical example of the phenomenon that we use for our empirical work.

I have also conducted research on innovation incentives in the context of Covid-19 vaccines and even the adoption of new market designs. I describe this latter problem as “Will the Market Fix the Market?”

Selected Materials

Research Papers

Missing Markets for Innovation: Evidence from New Uses for Existing Drugs

Coauthors: Maya Durvasula, Benjamin Roin, Heidi Williams
Draft: February 2026.
National Bureau of Economic Research Working Paper Series, no. 34222
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A Theory of Stock Exchange Competition and Innovation: Will the Market Fix the Market?

Coauthors: Robin Lee and John Shim
Journal of Political Economy, (2024): 132, no. 4, 1209-1246.
AEA/AFA Joint Luncheon Address, Will the Market Fix the Market? (January 2017)
Transcript, Will the Market Fix the Market?
Slides, Will the Market Fix the Market?
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Market Design to Accelerate Covid-19 Vaccine Supply

Coauthors: Juan Camilo Castillo, Amrita Ahuja, Susan Athey, Arthur Baker, Tasneem Chipty, Rachel Glennerster, Scott Duke Kominers, Michael Kremer, Greg Larson, Jean Lee, Canice Prendergast, Christopher M Snyder, Alex Tabarrok, Brandon Joel Tan, and Witold Więcek
Science, (2021): 68, no.2, 1107-1109.
Supplementary Materials
Bigger Is Better When It Comes to Vaccine Production
How Can More Covid-19 Vaccines be Made Available?
Management Conference ’21: Perspectives on COVID-19
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Patents and Research Investments: Assessing the Empirical Evidence

Coauthors: Benjamin J Roin and Heidi Williams
American Economic Review: Papers & Proceedings, (2016): 106, no. 5, 183-187.
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Do Firms Underinvest in Long-Term Research? Evidence from Cancer Clinical Trials

Coauthors: Benjamin J Roin and Heidi Williams
American Economic Review, (2015): 105, no. 7, 2044-2085.
Winner- the Kauffman/iHEA Award for Health Care Entrepreneurship and Innovation Research
Winner- the Arrow Award for "best paper published in health economics" in 2015
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